To determine the potential involvement of elevated TrkB expression in gastric cancer metastasis to distant organs, we compared TrkB mRNA expression levels between nonmetastatic (SNU-484 and SNU-719) and metastatic (SNU-16, SNU-620, NCI-N87, MKN45, and HTB135) gastric cancer cell lines. This evidence concerns the gene NTRK2 and gastric cancer.