Using the MeTA method, on the other hand, the spectrum of selected genes differs, because this method upregulates hypermethylated genes without DNA demethylation; Aza‐CR upregulated genes classified as cancer/testis (CT) antigen such as MAGE (melanoma antigen), GAGE (G antigen), and XAGE (X antigen), whereas MeTA did not upregulate these genes 15. Here, UAP1 is linked to cancer.