CCN1 and metastatic malignant neoplasm in the lymph nodes: Further analyses found that the expression of Cyr-61 was closely associated with invasion depth (p = 0.027), lymph node metastasis (p = 0.001), distant metastases (p = 0.045), poor histological differentiation (p = 0.031), and advanced TNM staging (p = 0.009).