ZEB1 and lung carcinoma: Recent studies have shown that ZEB1 acts as an oncogene in invasive and metastatic lung cancer cells, in which ZEB1-induced EMT promotes the loss of epithelial cell polarity and adhesion, induces cytoskeleton remodelling and drives growth, migration, invasion and metastasis5, 6, 7, 8, 9, 10, 11.