To explore the role of such EMT-promoting factors in lung carcinogenesis, we mined the Oncomine data sets of lung adenocarcinomas (nine data sets from www.oncomine.org) for alterations in CDH1, VIM, ZEB1, ZEB2, SNAI1, SLUG (also known as SNAI2) and TWIST (Table 1). The gene discussed is ZEB1; the disease is lung adenocarcinoma.