The clinical relevance of these findings is further supported by an analysis of The Cancer Genome Atlas (TCGA) (www.cancergenome.nih.gov) lung adenocarcinoma data set (n=510), in which ZEB1 negatively correlated with ERBB3 (Pearson's R=−0.24, P=6.94E−08). Here, ERBB3 is linked to lung adenocarcinoma.