BRCA1 and pachyonychia congenita: Our patient cohort is included in the recently published data on the initial screening round of the IMPACT [15] (Identification of Men with a genetic predisposition to ProstAte Cancer: Targeted screening in BRCA1/2 mutation carriers and controls; www.impact-study.co.uk) Study, supporting the notion that men with BRCA1/2 gene mutations are at increased risk of developing PC.