TGFB1 and hepatocellular carcinoma: The whole genome and transcriptomic analyses reveal that somatic mutations in genes involved in VD metabolism and VD-related genes occur frequently in hepatocellular cancers correlating with the TGF-β superfamily, suggesting that combined inactivating somatic mutations in VD-related genes and the TGF-β signaling members play a critical role in liver tumorigenesis.