COL8A2 and cranioectodermal dysplasia: A genetic basis for FECD is well established in human patients with mutations in COL8A2,17,18LOXHD1,19SLC4A11,20TCF4,21 and TCF822 reported to affect the collagen secretion or water pump functions of the endothelium.23 To the author's knowledge, there are no published reports evaluating the genetics of canine CED.