Novel information provided by the current report includes: 1) GROa, IL8, IL15 and follistatin are myokines whose secretion is higher in T2D, 2) secretion of IL1ß and VEGF is similar between ND and T2D myotubes, and, 3) IL10 secretion by resting myotubes is modest. This evidence concerns the gene IL1B and type 2 diabetes mellitus.