We show, however, that a positive iDNA score was associated with better overall survival (HR = 3.17 [1.18–8.51], p = 0.022) in Her2+ breast cancer (Fig. 3b), but not in hormone positive, Her2 negative (HR+/Her2−) or TNBC (Supplementary Fig. S3). Here, ERBB2 is linked to breast cancer.