ANK3 and Cowden disease: Except for ANK3 [ankyrin 3], ARHGAP39 [Rho GTPase activating protein 39], LILRA3 [leukocyte immunoglobulin-like receptor, superfamily A (without TM domain), member 3] and CSGALNACT1 (chondroitin sulfate N-acetylgalactosaminyltransferase 1] other Pediatric CD specific loci were not replicated (p ≤ 0.05) in Adult CD.