We also integrated known CBX7-regulated genes with genes overexpressed upon miR-375 in the RNA-Seq data set (Supplementary Table S2), and found the same activated pathways (Supplementary Figure S7), indicating that the activation of these pathways by CBX7 knockdown is mediated by miR-375 in prostate cancer cells. The gene discussed is CBX7; the disease is prostate carcinoma.