CBX7 and cancer: We integrated known CBX7 targets [36, 37] with genes upregulated following CBX7 knockdown in LNCaP cells from the microarray analysis (Supplementary Table S6, E-MTAB-3730) and found activation of prominent cancer pathways such as epithelial to mesenchymal transition (EMT) and Wnt/β-catenin signaling pathways (Figure 7D).