Adenoviral-mediated NF-ĸB2/p52 expression in LNCaP cells enhances tumor growth in intact male nude mice and induces tumor growth in castrated male nude mice, suggesting that NF-ĸB2/p52 overexpression induces androgen-independent growth of androgen-sensitive LNCaP cells [19]. This evidence concerns the gene NFKB2 and neoplasm.