For example, miR-138 modulates metastasis and EMT in breast cancer cells by targeting vimentin [7], miR-122 regulates hypoxia-inducible factor-1 and vimentin in hepatocytes [47], miR-141 downregulates the expression of vimentin in renal tubular epithelial cells [48], and miR-200c suppresses vimentin [49, 50]. This evidence concerns the gene VIM and breast cancer.