Downregulation of these proteins and weak upregulation of the differentiation markers glial fibrillary acidic protein (GFAP) and βIII-tubulin in the p53-proficient GBM-SCs was usually found 3–5 days after the combination treatment (Figure 1A) and later (Figure S2A and S2C). Here, TP53 is linked to glioblastoma.