KLRK1 and neoplasm: NKG2D+ NK cells were found significantly increased in peripheral lymphoid organs of the allogeneic mice inoculated with RAE-1 high expressing GL261 cells, not NKG2DL low expressing B16 cells (Figure 2A), suggesting that the NKG2DL high expressing tumor cells could mobilize the NKG2D+ NK cells to eliminate the tumor cells.