In all sections of AD hippocampus examined (but never in AMC), we observed abundant PLA signal for tau in close proximity to Aβ1–42 oligomers (Figs 4 and 5) in puncta that counter‐stained for the autophagosome marker LC3B/ATG8 (Fig. 5), consistent with their co‐aggregation in AD neurons. This evidence concerns the gene MAP1LC3B and Alzheimer disease.