Two miRs, miR-630 and miR-150-5p, are up- and down-regulated respectively, in all JMML molecular subtypes more than 2 fold, while miR-1260, miR-146b-5p and miR-4454 were downregulated in both KRAS and NRAS mutants only. The gene discussed is NRAS; the disease is juvenile myelomonocytic leukemia.