Next, we overexpressed miR-150-5p mimic or control oligonucleotides in three different AML cell lines (K562, OCI-AML-3 and KG1a) that do not express miR-150-5p, using nucleoporation as described in Methods, and measured STAT5b mRNA and protein expression. The gene discussed is STAT5B; the disease is acute myeloid leukemia.