PIK3C3 and B-cell chronic lymphocytic leukemia: (Figure 3B) Similarly, in Namalwa (Burrkit lymphoma) and MEC-2 cells (CLL), 10 μM of Vps34-IN-1 and 3.3 and 10 μM of CAL-101, respectively, together synergistically caused significant inhibition of cell growth/viability.