To investigate whether the expression of RRBP1 was affected during cellular stress, we measured the endogenous protein and mRNA levels of RRBP1 in human hepatocellular carcinoma cells (Bel7402) treated with paclitaxel (PTX) and adriamycin (ADM), which are applied as chemotherapy drugs in cancer. Here, RRBP1 is linked to hepatocellular carcinoma.