At the same time, in lung adenocarcinoma samples, LFA-1 expression was also clearly upregulated in metastatic regions (Figure 2G–2H and 2J–2K), whereas ICAM-1 was detected primarily at the intersection between tumour cells and brain parenchyma (Figure 2I and 2L). The gene discussed is ICAM1; the disease is lung adenocarcinoma.