ITGAX and neoplasm: We examined clearance of YFP+ uracil auxotrophs from invaded CD11c+ cells in the ID8DV tumor microenvironment and observed a 16.8-fold and 12.9-fold reduction in the absolute number or percentage, respectively, of YFP+CD11c+ antigen presenting cells between 18 h and 66 h after therapeutic vaccination (Fig 4F).