AC, adenocarcinoma; AUC, area under the curve; CK19, cytokeratin 19; CRC, colorectal cancer; FFPE, formalin-fixation paraffin-embedding; HE, Haematoxylin and Eosin; IHC, immunohistochemistry; IQR, interquartile range; ITC, isolated tumour cells; LN, lymph node; OSNA, one-step nucleic acid amplification; pT, tumour stage; ROC, receiver-operator characteristic; RT-LAMP, reverse transcription loop-mediated isothermal amplification; TTL, total tumour load. Here, KRT19 is linked to neoplasm.