CXCL8 and infection: Whereas, infection with EDL933 wt, ΔescN, and Δstx showed a significant induction of hBD2 (48.6 ± 12.3 fold for wt, 60.5 ± 15.6 fold for ΔescN, and 41.5 ± 8.3 fold for Δstx) and IL-8 (5.6 ± 1.3 fold for wt, 7.5 ± 1.2 fold for ΔescN, and 4.9 ± 0.3 fold for Δstx) expression vs. NI controls, no significant effect was observed in EDL933 ΔfliC-infected cells (Figure 3A).