CXCL8 and infection: For infections with 85–170, all strains significantly increased expression of hBD2 (195.9 ± 50.1 fold for wt, 168.6 ± 40.4 fold for Δhcp, and 163.4 ± 26.8 fold for ΔlpfA1) and IL-8 (84.3 ± 21.8 fold for wt, 157.5 ± 45.7 fold for Δhcp, and 88.4 ± 28.0 fold for ΔlpfA1) vs. NI controls (Figure 3B).