IBSP and ocular melanoma: Furthermore, even if in our hands OM-HPBCs showed a higher expression of bone sialoprotein gene (IBSP) and a higher production of type I collagen fibers, no differences in internalization and survival of S. aureus inside SM- and OM-HPBCs could be seen, suggesting that S. aureus also uses mechanisms of internalization to invade HPBCs that are independent from the bone extracellular matrix.