CASP3 and cardiac arrest: Data from swine models showed that Shenfu can alleviate the cardiac dysfunction after cardiac arrest by improving energy delivery and alleviation of oxygenation and lipid peroxidation; in addition, there is some additional evidence that Shenfu can inhibit the expression of Bcl-2, Bax, and caspase-3, decrease apoptosis, alleviate injuries to the heart [28], decrease cardiac β-adrenergic receptor sensitivity [29], and be generally cardioprotective.