ATP1A2 and alternating hemiplegia of childhood: Of note, two ATP1A2 mutations were identified in patients with AHC, such as the I589T mutation reported in an atypical case of AHC (Al-Bulushi et al., 2014), and T378M, which was found in two families, either correlated with FHM (Bassi et al., 2004) or with AHC (Swoboda et al., 2004).