Here DAPK1 seems to be a promising target for drug development, especially with the aim of preventing the neuronal apoptosis after stroke as it has a central role in neuronal cell death (Bialik and Kimchi, 2004) and represents a relatively unique enzyme in the protein kinase superfamily whose biological functions are related to both signal-mediated apoptosis and autophagy (Stevens and Hupp, 2008). Here, DAPK1 is linked to Stroke.