DAPK1 and Alzheimer disease: In terms of a possible role in AD, two single nucleotide polymorphisms (SNPs) i.e., rs4878104 and rs4877365 are identified through the genotyping of chromosome 9 in more than 2000 AD patients, located within human DAPK1, suggested that the genetic variation in DAPK1 modulates susceptibility to LOAD (Li et al., 2006).