The expression of Notch3 and pS6 was higher in serous cystadenocarcinoma, lymph node metastasis, and ascites than in mucinous cystadenocarcinoma (p < 0.01, p < 0.05) and in the absence of lymph node metastasis (p < 0.01, p < 0.01) and ascites (p < 0.01, p < 0.01). This evidence concerns the gene NOTCH3 and metastatic malignant neoplasm in the lymph nodes.