IL4 and asthma: Naringin (37), a component isolated from the dried unripe or ripe fruit peel of Citrus grandis “tomentosa” (Exocarpium Citri Grandis), reduced enhanced cough and airway hyperresponsiveness and inhibited the increases in the leukocytes, IL-4, IL-5, and IL-13, in BALF in a model of asthma using guinea pigs [70].