High ApoA-I concentration is associated with increased risk of cancer, in particular head and neck squamous cell carcinoma [18], whereas the prognostic roles of ApoA-I, Apo-B, HDL-C, low-density lipoprotein cholesterol (LDL-C), total cholesterol (TC), and triglycerides (TG) remain unclear. The gene discussed is APOA1; the disease is cancer.