For example, the half-life of cetuximab, a chimeric monoclonal antibody targeting the epithelial growth factor receptor (EGFR) and clinically approved for treatment of several cancer types, is between 3.1 and 7.8 days in humans, whereas the half-life of a small molecule drug targeting the same molecule EGFR is only 36 h, requiring a different dosing scheme (Imai and Takaoka 2006). This evidence concerns the gene EGFR and cancer.