CD40LG and inflammatory bowel disease: In contrast to the decreased levels found in the plasma of patients with NAFLD, slightly higher P1-specific IgM titers were found in the plasma of patients classified with high activity IBD (score 3) compared to patients with inactive disease (score 0) (31,052 versus 21,121 RLU/100 ms, p = 0.0383, Fig. 5e).