However, deregulation of Rac1 signaling can have detrimental effects since Rac1-driven cellular processes are also involved in a number of pathological conditions, including cancer,4-6 cardiovascular diseases,7 neurodegenerative disorders,8 pathological inflammatory responses,9,10 kidney disorders11-16 and infectious diseases.17-19. The gene discussed is RAC1; the disease is cardiovascular disorder.