PLOD2 and osteogenesis imperfecta: Interestingly, collagen telopeptidyl hydroxylation, catalyzed by FKBP65-dependent LH2 (PLOD2), was increased despite the reduction in FKBP10 transcripts and FKBP65 protein to the level of type XI OI carriers (OMIM #610968, Fig 5A–5C, Table 1) [30].