MSX1 and Behcet disease: Interestingly, seven DMRs are located within the major histocompatibility complex (MHC; P‐value range: 1.81×10−7–4.79×10−4), a region that has been implicated in the pathogenesis of schizophrenia and BD.43, 51 Amongst the other DMRs identified, a region of hypermethylation encompassing an intronic and exonic region of Msh Homeobox 1 (MSX1; P=1.81×10−6) is noteworthy in light of previous evidence for altered methylation of this gene in BD and schizophrenia.52