Quantitative real-time polymerase chain reaction (qRT-PCR) results revealed that compared with peritumoral tissues (PTs), mRNA expression of SYNJ2BP in HCC tissues were significantly lower and the median fold-change was 0.23 (range, 0.01–1.28) (Fig. 1a). The gene discussed is SYNJ2BP; the disease is hepatocellular carcinoma.