Through Chi-square test we found that SYNJ2BP low expression level was significantly associated with large tumor size(P = 0.002), multiple tumor nodules (P < 0.001), vascular invasion(P < 0.001), high TNM stage(P < 0.001) and high BCLC stage(P = 0.001) (Table 1), which belonged to poor clinicopathological features of HCC. Here, SYNJ2BP is linked to neoplasm.