ROR2 and colorectal carcinoma: When cellular migration was examined in RKO and SW620 cells using wound healing assays, there was no significant change detected between the rate of wound closure between cells with and without ectopic ROR2 expression (Fig. 4c-f), indicating that although ROR2 knockdown may resulted in functional changes to CRC cell lines, the same may not be true with ectopic ROR2 expression.