Malhotra et al. investigated the concentrations of soluble endoglin, soluble vascular endothelial growth factor receptor-1 (sVEGFR1), N-terminal brain natriuretic peptide (NTproBNP), C-reactive protein (CRP), and other biomarkers in peripheral blood in 97 patients with PAH. The gene discussed is NPPB; the disease is pulmonary arterial hypertension.