Given its cancer-centric overexpression, FRα has been an attractive candidate for targeted drug delivery using folate-conjugated therapeutic compounds that bind FRα or murine, chimeric, and humanized monoclonal antibodies (mAbs) alone or in conjugates to deliver radionuclides, T cells, and stimulatory cytokines to malignant tissue [7, 8]. The gene discussed is FOLR1; the disease is cancer.