Among these target genes, the expression of BDNF [20], MEIS1 [38], FOXC1 [18], NUAK1 [40], RAB22A [42], and XRN1 [23] is inversely correlated with that of miR-204 in those tumor specimens examined, strongly suggesting that miR-204 is one of the key suppressors of the target genes. Here, XRN1 is linked to neoplasm.