Inhibition of MYCN in the Kelly cell line induced cell death as measured by trypan blue exclusion (Figure S1D) and similarly, although to a lesser extent, MYCN cell viability was diminished with siRNA treatment in both SHEP WT and SHEP T58/S62 neuroblastoma cell lines (Figure S1E, F), confirming that exogenous MYCN expression is responsible for the increased proliferation observed in SHEP WT and SHEP T58/S62 cells. The gene discussed is MYCN; the disease is neuroblastoma.