CD34 and chronic myelogenous leukemia, BCR-ABL1 positive: The IC50 of IB was similar in each of these cell contexts at 1.32 ± 0.25 μM for CD34+ CML-CP cells (n = 3) (Figure 1A), 1.13 ± 0.07 μM for KCL22WT cell line (Figure 1B), and approximately 1.65 μM for imatinib resistant KCL22T315I cells (Supplementary Figure S1A).