The effects of dasatinib and PKI-587 on cell proliferation and the extent of tumor apoptosis were assessed by IHC staining of human Ki-67 (Zymed Laboratories, San Francisco, CA, USA) and terminal deoxynucleotidyl transferase-mediated nick-end labeling (TUNEL) assays, respectively. The gene discussed is MKI67; the disease is neoplasm.