In contrast to these associations, the association of the TCF7L2rs7903146,SLC2A2rs11920090PRC1rs8042680, and PROX1rs340874 SNPs with OS was driven by diabetogenic alleles, which suggested that the effect of these variants on OS might be explained by their regulatory effect on insulin secretion and, consequently, on cell proliferation and tumour cell growth. Here, INS is linked to neoplasm.