KLK3 and Sepsis: Group B comprised 220 patients that received three doses of 500 mg levofloxacin orally, with an average age of 67.45 years (±8.31) and PSA mean of 21.26 ng/mL; 31.8% of patients have DM and 4.45% presented febrile urinary tract infection, in the same manner as in Group A; the body predominant in urine culture was E. coli; no patients in this group presented sepsis; mean prostate volume was 75.61 cc, of this group of patients; 72.74% had been overweight; in both groups the antibiotic was changed according to the antibiogram.