Heterogeneous nuclear ribonucleoprotein D0 (hnRNP D0), also known as AU-rich element RNA-binding protein 1 (AUF1), is a well-characterized ARE-binding factor that destabilizes mRNA, while human (Hu) antigen proteins of the ELAV (embryonic lethal, abnormal vision) family are known to stabilize mRNA. The gene discussed is HNRNPD; the disease is Abnormality of vision.