Compared to those with MMP1 ≤ 9.67 ng/mL, ESCC patients with MMP1 > 9.67 ng/mL had a 48% increase in the risk of ESCC death (adjusted hazard ratio = 1.48; 95% CI = 1.04–2.10) after adjusted for other covariates (Table 3). The gene discussed is MMP1; the disease is esophageal squamous cell carcinoma.