Functionally, we found that LPCAT activity in SCD mouse erythrocytes was significantly inhibited in a dosage-dependent manner by 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl) dodecanamide (CI-976), one of the most commonly used specific LPCAT inhibitors28, 29 (Supplementary Fig. 1e). This evidence concerns the gene LPCAT1 and Schnyder corneal dystrophy.