TNFRSF13C and common variable immunodeficiency: Mutations in TNFRSF members can also lead to common variable immunodeficiency (CVID): approximately 9 % of patients carry one or two variant alleles of TNFRSF13B (encoding TACI) [10] and a few patients carry biallelic mutations of TNFRSF13C (encoding BAFF-R) [11].