PACAP inputs to CeL originate in the parabrachial nucleus, which also projects to BNST-AL.86 However, PACAP inputs to BNST-AL are concentrated in the oval nucleus where they target CRF neurons.87 Given the rapidly accumulating evidence implicating PACAP and CRF signaling in PTSD,88 it will be important to characterize the excitability of CRF neurons of the oval nucleus in the Lewis rat model of PTSD. Here, ADCYAP1 is linked to post-traumatic stress disorder.